Not a same-day fix
NAD+ replenishment is cumulative. Most benefits show up with consistent daily use over weeks.
NAD PLUS™ Science / Benefits
The Benefits of NAD+ Support
What daily NAD+ replenishment is designed to support, and what the research actually says.
Benefit 1
Sustained Cellular Energy
Because your cells need NAD+ to turn food into ATP.
NAD+ is a coenzyme used in many of the chemical reactions that convert nutrients into ATP, the molecule your cells actually spend to do everything from move muscles to think. When NAD+ is available, those reactions run smoothly.
In a triple-blind, placebo-controlled clinical trial published in Nutrients (2022), RiaGev® was associated with increases in markers of cellular energy production, including high-energy phosphates, alongside increases in NAD+.
Steadier day-long energy versus the crashes many people describe after 35.
Source: Xue Y, et al. Nutrients. 2022;14:2219; Bioenergy Life Science RiaGev® White Paper, 2022.
Trial markers shown as associated with RiaGev®. Illustrative and simplified.
Benefit 2
Antioxidant Defense
NAD+ is linked to glutathione, your body's master antioxidant.
Glutathione is produced by every cell in your body and is central to how cells balance oxidative stress and support detoxification processes. NAD+ and glutathione work together as part of the redox system.
In the published RiaGev® clinical trial, participants showed increases in total glutathione alongside increases in NAD+, an outcome that is uncommon for supplements that target NAD+ alone.
Supporting NAD+ and supporting antioxidant defense are not two separate things. They are part of the same cellular system.
Source: Xue Y, et al. Nutrients. 2022;14:2219; Bioenergy Life Science RiaGev® White Paper, 2022.
Both reported together in the RiaGev® trial. Illustrative.
Benefit 3
Healthy Aging Support
NAD+ replenishes what naturally declines over time.
NAD+ depletion has been linked to mitochondrial dysfunction, a recognized hallmark of aging. Restoring NAD+ availability is one of the most researched approaches in the healthy-aging category.
ReVive is a healthy-aging supplement. It is designed to support how well your cells function over time, not to reverse aging.
Source: Bioenergy Life Science RiaGev® White Paper, 2022; Summary of the History of B3 in Wellbeing (literature review).
Illustrative only. Individual NAD+ levels vary.
Benefit 4
Focus and Mental Clarity
Cellular energy shows up in the way your mind feels.
Your brain is one of the most energy-demanding tissues in your body. It depends on the same NAD+/ATP system that runs the rest of your cells.
In the published RiaGev® clinical trial, participants reported improvements in mental concentration and motivation, and less fatigue, alongside the changes in cellular energy markers.
Fewer mid-day mental fog patches. Cleaner focus, without the caffeine spike-and-crash.
Source: Xue Y, et al. Nutrients. 2022;14:2219.
Reported by participants in the published trial. Illustrative.
Benefit 5
Recovery and Daily Resilience
When your cells have what they need, they bounce back faster.
Recovery, whether from a demanding workout, a stressful week, or just a long day, is a cellular process. The systems that repair and reset your cells rely on both NAD+ and ATP.
Supporting NAD+ helps ensure your cells have the raw materials they need for the maintenance work that happens overnight and between demands.
Recovery is not a nice-to-have. It is what allows sustained performance over time.
Illustrative and simplified.
Straight talk
What These Benefits Do Not Mean
Being direct about expectations.
Not a stimulant
There is no caffeine spike, and no crash. This works at the cellular level, not the nervous system.
Not a treatment
This is a supplement designed to support cellular health. It is not intended to diagnose, treat, cure, or prevent any medical condition.
Not a replacement for good basics
NAD+ support works alongside sleep, movement, and nutrition, not instead of them.
Not identical for everyone
Individual experience varies. That is why consistency and honest self-observation matter.
Is this for you?
Who This Is For
People noticing a shift in day-to-day energy
Especially adults in their 30s, 40s, and beyond, when NAD+ decline typically becomes noticeable.
People interested in healthy aging as a system
Not chasing a single fix, but supporting the underlying processes that shape how you feel over time.
People who prefer daily consistency to spike-and-crash
Whether that means avoiding caffeine dependence or looking for a steadier alternative to fast-release supplements.
People who want cellular support alongside the basics
Supplementation as a complement to sleep, movement, and nutrition, not a substitute.
Questions
Frequently Asked Questions
When will I start feeling the benefits?
Individual experience varies. Many people describe noticing changes in energy and focus within a couple of weeks of consistent daily use. NAD+ replenishment is a cumulative process, so benefits generally build over time.
Are these benefits guaranteed?
No supplement can guarantee outcomes. The benefits described are based on published research on RiaGev® and on the broader NAD+ literature. Individual results vary based on age, health, and lifestyle.
Is this the same as an “anti-aging” supplement?
ReVive is a healthy-aging supplement. It is designed to support how your cells function over time. It is not designed to reverse aging or produce cosmetic outcomes.
Do I need to take it forever?
NAD+ is consumed continuously by your cells. If you stop supplementing, your NAD+ levels will follow whatever their natural trajectory would have been. Whether to continue is a personal choice; we recommend consulting your healthcare provider.
Recognition
Industry-Recognized for Innovation.
NIE 2020 Gold Winner
Recognized for innovation and excellence in nutraceutical ingredients at the Nutrition Industry Executive Awards.
2024 Ingredient Idol Finalist
Selected by Natural Products Insider (SupplySide Global) as one of the most innovative new ingredients in health and wellness.
Where you'll find RiaGev® in NAD PLUS
Sustained-Release, All Day.
Go deeper
Keep Exploring the Science
The ingredient
Meet RiaGev®
The patented NAD+ builder inside ReVive, and the clinical data behind it.
Read the ingredient page
The benefits
Healthy agingThe Benefits of NAD+ Support
What daily NAD+ replenishment is designed to support, and what the research says.
You're hereNAD+ and Aging
Why NAD+ levels change with age, and what that means for how you feel.
Cellular biologyNAD+ and Mitochondria
Why the power plants inside your cells depend on NAD+ to work well.
Cellular energyNAD+ and Cellular Energy
Why your cells need NAD+ to produce energy, and what changes as we age.
The comparisonNAD+ vs. NMN
What's the difference, and why we built ReVive around the salvage pathway.
Safety
Safety Starts with Your Provider.
Consult your provider
If you're pregnant, nursing, taking medications, or managing a medical condition, talk to your healthcare provider before starting any new supplement.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
References
Published Literature & Source Documents.
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Bioenergy Life Science. RiaGev® White Paper. 2022.
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Bioenergy Life Science. RiaGev® Long-Term Trial White Paper. 2022.
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Pharmacodynamics Study Summary of RiaGev™. American Preclinical Services and Bioenergy Life Science. March 28, 2019.
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Summary of the History of B3 in Wellbeing (literature review).